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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sanchez, Livan | RP | Mobile BayBears | 21 | 10/21/1997 | Santo Domingo | DOM | Left | Left | 6' 0" | 165 lbs | - |
| Sanchez, Lolo | CF | Harrisburg Senators | 19 | 04/23/1999 | Santo Domingo | DOM | Right | Right | 5' 10" | 170 lbs | - |
| Sanchez, Sixto | SP | Mississippi Braves | 20 | 07/29/1998 | San Cristóbal | DOM | Right | Right | 6' 0" | 185 lbs | - |
| Sanchez, Tyler | 1B | Pensacola Blue Wahoos | 25 | 05/30/1993 | Port St. Lucie | USA | Right | Right | 6' 2" | 190 lbs | - |
| Sandlin, Nick | CL | Hartford Yard Goats | 21 | 01/10/1997 | Evans | USA | Right | Right | 5' 10" | 170 lbs | - |
| Santana, Dennis | SP | Biloxi Shuckers | 22 | 04/12/1996 | San Pedro de Macorís | DOM | Right | Right | 6' 2" | 160 lbs | - |
| Saucedo, Tayler | SP | Montgomery Biscuits | 25 | 06/18/1993 | Honolulu | USA | Left | Left | 6' 5" | 185 lbs | - |
| Sauer, Matt | SP | Erie SeaWolves | 19 | 01/21/1999 | Santa Maria | USA | Right | Right | 6' 3" | 195 lbs | - |
| Sawyer, Dalton | SP | Pensacola Blue Wahoos | 24 | 11/22/1993 | Waconia | USA | Left | Left | 6' 5" | 210 lbs | - |
| Scheetz, Kit | RP | Bowie Baysox | 24 | 05/18/1994 | Richmond | USA | Left | Left | 5' 10" | 185 lbs | - |
| Scheiner, Jake | 3B | Bowie Baysox | 23 | 08/13/1995 | Santa Rosa | USA | Right | Right | 6' 0" | 200 lbs | - |
| Scherff, Alex | SP | Altoona Curve | 20 | 02/05/1998 | Colleyville | USA | Switch | Right | 6' 3" | 205 lbs | - |
| Schmidt, Clarke | SP | Trenton Thunder | 22 | 02/20/1996 | Acworth | USA | Right | Right | 6' 0" | 200 lbs | - |
| Schroeder, Casey | C | Midland RockHounds | 25 | 07/12/1993 | Ottawa | USA | Switch | Right | 6' 2" | 225 lbs | - |
| Schryver, Hunter | RP | Bowie Baysox | 23 | 04/03/1995 | Mechanicsburg | USA | Left | Left | 6' 0" | 200 lbs | - |
| Schultz, Jaime | RP | Harrisburg Senators | 27 | 06/20/1991 | Albany | USA | Right | Right | 5' 10" | 200 lbs | - |
| Seabold, Connor | SP | Montgomery Biscuits | 22 | 01/24/1996 | Newport Beach | USA | Right | Right | 6' 3" | 190 lbs | - |
| Seijas, Alvaro | RP | Northwest Arkansas Naturals | 20 | 10/10/1998 | Maracay | VEN | Right | Right | 6' 0" | 175 lbs | - |
| Seise, Chris | 3B | Midland RockHounds | 19 | 01/06/1999 | Winter Garden | USA | Right | Right | 6' 2" | 175 lbs | - |
| Sellers, Donnie | RP | Altoona Curve | 23 | 07/26/1995 | High Point | USA | Right | Right | 6' 0" | 190 lbs | - |
| Senior, Eric | LF | Trenton Thunder | 21 | 09/29/1997 | Toronto | CAN | Right | Right | 6' 2" | 170 lbs | - |
| Sepulveda, Carlos | 2B | San Antonio Missions | 22 | 08/27/1996 | Monclova | MEX | Left | Right | 5' 10" | 170 lbs | - |
| Serrano, Kyle | SP | Bowie Baysox | 23 | 07/06/1995 | Knoxville | USA | Right | Right | 6' 0" | 190 lbs | - |
| Sexton, Austin | RP | Reading Fightin Phils | 24 | 07/17/1994 | Madison | USA | Right | Right | 6' 2" | 185 lbs | - |
| Shumpert, Nick | 2B | Hartford Yard Goats | 21 | 11/11/1996 | Lone Tree | USA | Right | Right | 5' 10" | 180 lbs | - |
| Sierra, Miguelangel | 2B | Pensacola Blue Wahoos | 20 | 12/02/1997 | Altagracia de Orituco | VEN | Right | Right | 5' 10" | 165 lbs | - |
| Skoglund, Eric | SP | Jacksonville Jumbo Shrimp | 26 | 10/26/1992 | Sarasota | USA | Left | Left | 6' 7" | 210 lbs | - |
| Skoug, Evan | 1B | Corpus Christi Hooks | 23 | 10/21/1995 | Libertyville | USA | Left | Right | 5' 10" | 200 lbs | - |
| Smith, Burch | RP | Free Agent | 28 | 04/12/1990 | Tyler | USA | Right | Right | 6' 3" | 225 lbs | - |
| Smith, Chad Wesley | LF | Altoona Curve | 21 | 09/30/1997 | Snellville | USA | Left | Left | 6' 2" | 200 lbs | - |
| Smith, Kevin | 2B | Richmond Flying Squirrels | 22 | 07/04/1996 | East Greenbush | USA | Right | Right | 6' 0" | 190 lbs | - |
| Smith, Ridge | C | Richmond Flying Squirrels | 23 | 04/26/1995 | Germantown | USA | Right | Right | 5' 10" | 190 lbs | - |
| Snelten, D.J. | RP | Pensacola Blue Wahoos | 26 | 05/29/1992 | Antioch | USA | Left | Left | 6' 5" | 240 lbs | - |
| Solomon, Peter | SP | Binghamton Rumble Ponies | 22 | 08/16/1996 | Ellicott City | USA | Right | Right | 6' 3" | 200 lbs | - |
| Sparks, Lamar | RF | Altoona Curve | 20 | 09/26/1998 | Katy | USA | Right | Right | 6' 2" | 170 lbs | - |
| Spitznagel, Ben | LF | Bowie Baysox | 24 | 08/30/1994 | Cincinnati | USA | Left | Right | 5' 10" | 170 lbs | - |
| Stephan, Trevor | SP | Chattanooga Lookouts | 22 | 11/25/1995 | Magnolia | USA | Right | Right | 6' 5" | 225 lbs | - |
| Stephenson, Tyler | C | Jacksonville Jumbo Shrimp | 22 | 08/16/1996 | Kennesaw | USA | Right | Right | 6' 3" | 225 lbs | - |
| Stiever, Jonathan | SP | Jackson Generals | 21 | 05/12/1997 | Cedarburg | USA | Right | Right | 6' 2" | 205 lbs | - |
| Stowers, Josh | LF | Trenton Thunder | 21 | 02/25/1997 | Westchester | USA | Right | Right | 6' 0" | 190 lbs | - |
| Strahan, Wyatt | RP | Harrisburg Senators | 25 | 04/18/1993 | Villa Park | USA | Right | Right | 6' 3" | 220 lbs | - |
| Strain, Connor | RP | Birmingham Barons | 24 | 08/04/1994 | Shelburn | USA | Right | Right | 6' 0" | 180 lbs | - |
| Stumpf, Daniel | RP | Jacksonville Jumbo Shrimp | 27 | 01/04/1991 | Humble | USA | Left | Left | 6' 2" | 210 lbs | $545,000 |
| Supak, Trey | SP | Akron RubberDucks | 22 | 05/31/1996 | Bryan | USA | Right | Right | 6' 5" | 235 lbs | - |
| Swanda, John | SP | Mobile BayBears | 19 | 03/18/1999 | Des Moines | USA | Right | Right | 6' 2" | 185 lbs | - |
| Sweet, Daniel | CF | Akron RubberDucks | 23 | 12/28/1994 | Brandon | USA | Switch | Left | 6' 0" | 190 lbs | - |
| Szapucki, Thomas | SP | Jackson Generals | 22 | 06/12/1996 | Palm Beach Gardens | USA | Right | Left | 6' 2" | 180 lbs | - |
