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| Name | W | L | SV | ERA | G | GS | IP | HA | R | ER | HR | BB | K | WHIP | OAVG | BABIP | WAR |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Brent Suter SP | 0 | 0 | 0 | 0.00 | 3 | 0 | 7.0 | 3 | 0 | 0 | 0 | 1 | 8 | 0.57 | .130 | .200 | 0.3 |
| Gregory Infante RP | 1 | 5 | 12 | 1.99 | 47 | 0 | 49.2 | 32 | 12 | 11 | 3 | 24 | 61 | 1.13 | .180 | .254 | 1.3 |
| Kris Medlen RP | 1 | 0 | 0 | 2.45 | 8 | 0 | 11.0 | 9 | 5 | 3 | 1 | 4 | 9 | 1.18 | .214 | .250 | 0.1 |
| Trevor Cahill SP | 2 | 1 | 0 | 2.48 | 34 | 3 | 54.1 | 41 | 16 | 15 | 2 | 26 | 56 | 1.23 | .214 | .283 | 1.0 |
| Daniel Hudson RP | 2 | 2 | 6 | 2.75 | 19 | 0 | 19.2 | 12 | 6 | 6 | 2 | 9 | 22 | 1.07 | .171 | .217 | 0.5 |
| Sean Manaea SP | 7 | 6 | 0 | 2.75 | 18 | 18 | 111.1 | 91 | 37 | 34 | 13 | 34 | 71 | 1.12 | .226 | .241 | 1.5 |
| Brandon McCarthy RP | 7 | 8 | 0 | 3.96 | 32 | 26 | 150.0 | 160 | 68 | 66 | 16 | 38 | 101 | 1.32 | .274 | .307 | 2.3 |
| Peter Moylan RP | 5 | 5 | 5 | 4.08 | 83 | 0 | 75.0 | 68 | 35 | 34 | 9 | 30 | 57 | 1.31 | .244 | .274 | 0.2 |
| Matt Wisler SP | 0 | 0 | 0 | 4.15 | 2 | 0 | 4.1 | 3 | 2 | 2 | 1 | 3 | 3 | 1.38 | .200 | .182 | -0.1 |
| Miles Mikolas SP | 7 | 16 | 0 | 4.22 | 34 | 34 | 196.1 | 203 | 102 | 92 | 22 | 74 | 144 | 1.41 | .267 | .299 | 2.6 |
| Enny Romero RP | 1 | 1 | 1 | 4.46 | 34 | 0 | 34.1 | 32 | 19 | 17 | 5 | 16 | 34 | 1.40 | .237 | .276 | 0.1 |
| Marco Estrada SP | 6 | 13 | 0 | 4.67 | 35 | 26 | 169.2 | 173 | 89 | 88 | 36 | 47 | 114 | 1.30 | .266 | .271 | -0.1 |
| Taijuan Walker SP | 4 | 14 | 0 | 4.77 | 34 | 34 | 185.0 | 206 | 107 | 98 | 21 | 64 | 132 | 1.46 | .283 | .318 | 2.3 |
| Mark Leiter Jr. SP | 2 | 4 | 0 | 5.05 | 11 | 11 | 51.2 | 57 | 31 | 29 | 9 | 19 | 53 | 1.47 | .281 | .336 | 0.4 |
| Jason Vargas SP | 0 | 1 | 0 | 5.40 | 1 | 1 | 5.0 | 5 | 3 | 3 | 0 | 4 | 5 | 1.80 | .263 | .357 | 0.1 |
| James Shields SP | 3 | 5 | 0 | 5.50 | 39 | 5 | 68.2 | 82 | 50 | 42 | 11 | 30 | 59 | 1.63 | .296 | .343 | 0.0 |
| Zach Duke RP | 5 | 3 | 0 | 5.72 | 51 | 0 | 45.2 | 49 | 32 | 29 | 6 | 27 | 57 | 1.66 | .274 | .371 | 0.2 |
| Brian Johnson RP | 8 | 4 | 3 | 5.87 | 70 | 4 | 110.1 | 125 | 75 | 72 | 15 | 41 | 80 | 1.50 | .286 | .318 | 0.1 |
| Michael Lorenzen RP | 2 | 5 | 3 | 5.91 | 80 | 0 | 80.2 | 96 | 54 | 53 | 14 | 40 | 70 | 1.69 | .294 | .333 | -0.7 |
| Brandon Kintzler CL | 0 | 6 | 10 | 7.33 | 22 | 0 | 23.1 | 35 | 19 | 19 | 3 | 9 | 17 | 1.89 | .337 | .381 | 0.0 |
